Biostatistics Study NotesFrom concepts and derivations to interpretation

CHAPTER 01 · TOPIC 03

Descriptive Statistics

Summarize center, variability, skewness, and kurtosis with measures suited to the data distribution.

On this page
  1. Start with the data type
  2. Central tendency
  3. Trimmed and geometric means
  4. Variability: how different are the observations?
  5. Variance and standard deviation
  6. Coefficient of variation
  7. Distribution shape: skewness and kurtosis
  8. A complete descriptive report

Descriptive statistics organize, summarize, and display data. They help us understand what a sample contains, where its center lies, how widely it varies, whether its distribution is symmetric, and whether unusual observations are present.

Start with the data type#

Data typeTypical summariesTypical displays
CategoricalCounts and proportionsFrequency table, bar chart
NumericalMean and SD, or median and IQRHistogram, box plot, density plot

Central tendency#

The mode is the most frequent value and may be used for categorical or numerical data. The median is the middle ordered value and is resistant to extreme observations. The arithmetic mean uses every observation and is highly useful for inference, but is more sensitive to outliers.

Median position for odd nn+12\frac{n+1}{2}
Median for even nMedian=x(n/2)+x(n/2+1)2\operatorname{Median}=\frac{x_{(n/2)}+x_{(n/2+1)}}2
Arithmetic meanxˉ=1ni=1nxi\bar x=\frac1n\sum_{i=1}^{n}x_i

Trimmed and geometric means#

A trimmed mean removes a fixed proportion from both tails before averaging, providing a compromise between the mean and median. The geometric mean is appropriate for positive multiplicative quantities such as growth factors, ratios, and some log-normal measurements.

Product formG=(i=1nxi)1/n,xi>0G=\left(\prod_{i=1}^{n}x_i\right)^{1/n},\quad x_i>0
Log formG=exp ⁣(1ni=1nlnxi)G=\exp\!\left(\frac1n\sum_{i=1}^{n}\ln x_i\right)

A logarithm compresses large positive values and may make a right-skewed distribution more symmetric. Ordinary log transformation and the geometric mean are not directly defined when observations include zero or negative values.

Variability: how different are the observations?#

RangeRange=xmaxxmin\text{Range}=x_{\max}-x_{\min}
Interquartile rangeIQR=Q3Q1\operatorname{IQR}=Q_3-Q_1

The range uses only the extremes and is sensitive to outliers. The IQR describes the middle 50% of observations and pairs naturally with the median.

Variance and standard deviation#

Populationσ2=1Ni=1N(xiμ)2,σ=σ2\sigma^2=\frac1N\sum_{i=1}^{N}(x_i-\mu)^2,\qquad\sigma=\sqrt{\sigma^2}
Samples2=1n1i=1n(xixˉ)2,s=s2s^2=\frac1{n-1}\sum_{i=1}^{n}(x_i-\bar x)^2,\qquad s=\sqrt{s^2}

Variance averages squared distances from the mean. The standard deviation takes the square root and therefore returns to the original measurement unit. The n−1 denominator in sample variance reflects degrees of freedom and unbiased estimation.

Coefficient of variation#

CV=sxˉ×100%\operatorname{CV}=\frac{s}{\bar x}\times100\%

The CV expresses standard deviation relative to the mean. It is useful for positive ratio-scale measurements with meaningful zeroes, but is unstable or difficult to interpret when the mean is near zero or negative.

Distribution shape: skewness and kurtosis#

Skewness describes asymmetry. Its sign follows the longer tail: a long left tail gives negative skewness, while a long right tail gives positive skewness.

γ1=E ⁣[(Xμσ)3]=μ3σ3\gamma_1=E\!\left[\left(\frac{X-\mu}{\sigma}\right)^3\right]=\frac{\mu_3}{\sigma^3}

The third power preserves direction, allowing the sign to distinguish left from right skew.

Kurtosis is better understood as sensitivity to tail weight and extreme observations than simply as the sharpness of a peak.

β2=E ⁣[(Xμσ)4],γ2=β23\beta_2=E\!\left[\left(\frac{X-\mu}{\sigma}\right)^4\right],\qquad\gamma_2=\beta_2-3

Normal-distribution kurtosis β₂ is 3 and excess kurtosis γ₂ is 0. Software may report either definition, so always verify the convention.

A complete descriptive report#

  1. Identify the data type and measurement scale
  2. Report counts and proportions for categorical variables
  3. Report both center and variability for numerical variables
  4. Inspect plots and outliers before choosing mean/SD or median/IQR
  5. Use shape statistics and graphs when helpful, without judging a distribution from one number alone